
The bill was passed above the objections of President Woodrow Wilson, who used his veto to try to prevent prohibition from being enacted. But on October 27, 1919, Wilson's veto was overridden in the House of Representatives, the same day as the veto, and it was overridden in the Senate on October 28th.
The Eighteenth Amendment to the Constitution prohibited the production, sale, and transport of "intoxicating liquors", but it did not define what "intoxicating liquors" were, and it did not provide penalties for offenders. The Volstead Act gave both the federal government and the states the power to enforce the ban. Wilson's veto was based largely on technical grounds. Wilson was opposed to the bill because it also included prohibition during wartime.
As we now know, prohibition didn't work out as planned. The production, importation, and distribution of alcoholic beverages, once performed by legitimate businesses, were taken over by criminal gangs, which fought each other for market control in violent turf wars. Many gangsters became rich and were admired for flouting an unpopular law. Enforcement was difficult because the gangs became so rich they were often able to bribe underpaid and understaffed law-enforcement personnel and pay for expensive lawyers. They also were able to garner the support of many politicians by financing their campaigns. Many in higher socio-economic groups were inclined to flout the law. In large cities that served as major points of liquor importation (such as Chicago and Detroit) gangs wielded significant political power.
Prohibition came into force at midnight on January 17, 1920. In anticipation of its passage, some gang leaders were stashing liquor months before the Volstead Act was enforced. Enforcement of the Volstead Act was problem. There were only 134 agents designated by the Prohibition Unit to cover all of Illinois, Iowa, and parts of Wisconsin. According to Charles C. Fitzmorris, Chicago's Chief of Police during the beginning of the Prohibition period, 60% of his police force were in the bootleg business.

Prohibition lost advocates as alcohol gained increasing social acceptance and as prohibition led to disrespect for the law and the growth of organized crime. Congress passed the Blaine Act, a proposed constitutional amendment to repeal Prohibition, in February. On December 5, 1933, Utah became the 36th state to ratify the Twenty-first Amendment, which repealed the Eighteenth Amendment, rendered the Volstead Act unconstitutional, and restored control of alcohol to the states.